Protection Patterns of tRNAs Do Not Change during Ribosomal Translocation
نویسندگان
چکیده
منابع مشابه
Interictal epileptiform discharges do not change before seizures during sleep.
PURPOSE Whether interictal epileptiform discharges (IEDs) increase, decrease, or are unchanged before epileptic seizures has implications for the pathophysiology of epilepsy. Prior studies relating IEDs and seizures have not demonstrated a change in IEDs before seizures. However, they have not controlled for changes in the depth of sleep. Our objective was to test the hypothesis that IEDs are r...
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Fusidic acid does not inhibit the translocation of N-acetylphenylalanyl-tRNA (N-acetyl-Phe-tRNA), bound nonenzymitally to the ribosomal A-site, when the amount of ribosomes in the reaction mixture is not sufficient to trap all the available elongation factor G (EF-G) in the form of GDP ‘EF-G .fusidic acid .ribosome complexes. Moreover, since only those ribosomes in the reaction mixture that are...
متن کاملSpecificity of the ribosomal A site for aminoacyl-tRNAs
Although some experiments suggest that the ribosome displays specificity for the identity of the esterified amino acid of its aminoacyl-tRNA substrate, a study measuring dissociation rates of several misacylated tRNAs containing the GAC anticodon from the A site showed little indication for such specificity. In this article, an expanded set of misacylated tRNAs and two 2'-deoxynucleotide-substi...
متن کاملDynamic relationships between ribosomal conformational and RNA positional changes during ribosomal translocation
Ribosomal translocation catalyzed by EF-G hydrolyzing GTP entails multiple conformational changes of ribosome and positional changes of tRNAs and mRNA in the ribosome. However, the detailed dynamic relations among these changes and EF-G sampling are not clear. Here, based on our proposed pathway of ribosomal translocation, we study theoretically the dynamic relations among these changes exhibit...
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We compared joint proprioception in 12 hips in 12 patients with hemiarthroplasty after fracture of the hip, in 12 hips in 11 patients with total hip arthroplasty because of osteoarthritis and in a control group of 12 age-matched patients with no clinical complaints. There was no significant difference (p = 0.05) in joint proprioception in any of the groups. There was no decrease in joint propri...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1998
ISSN: 0021-9258
DOI: 10.1074/jbc.273.49.32793